Reference ID: 3084430
Infusion System User's Guide for the set up and intravenous infusion of rubidium Rb 82 chloride injection dose(s). 2.2 Rubidium Rb 82 Chloride Injection Dosage . The recommended adult single dose of rubidium Rb 82 chloride injection is 1480 MBq (40 mCi) with a range of . 1110-2220 MBq (30-60 mCi). Do not exceed a single dose of 2220 MBq …Web
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Cardiogen-82 (rubidium Rb 82 generator): Uses, Dosage, Side
The specific gamma ray constant for Rb-82 is 6.1 R/hour-millicurie at 1 centimeter. The first half-value layer is 0.7 centimeter of lead (Pb). Table 5 shows a range of values for the relative attenuation of the radiation emitted by this radionuclide that results from interposition of various thicknesses of lead. 5 For example, the use of a 7.0 …Web
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WO2022211675A3
Le générateur est destiné à la production d'une préparation radio-pharmaceutique avec du chlorure de 82Rb, qui est rincé à partir du sorbant puis introduit dans le corps du patient afin de diagnostiquer différentes maladies par tomographie à émission de positon; les isotopes de strontium-82 et 85 doivent rester sur le sorbant et ne ...Web
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EANM procedural guidelines for PET/CT quantitative
82 Rb has the same biological properties as potassium (K +) and is extracted by the myocardium through the Na-K-ATPase pump. 82 Rb is taken up in viable myocardium, whilst it is rapidly cleared from fibrotic tissue. The extraction of 82 Rb during the first pass is high (65%) but decreases in a non-linear way with increasing blood flow …Web
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Frontiers | Story of Rubidium-82 and Advantages for …
Rubidium-82 has a long story, starting in 1954. After preclinical studies in dogs showing that myocardial uptake of this radionuclide was directly proportional to myocardial blood flow (MBF), clinical studies were …Web
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Facts About Rubidium | Live Science
Atomic number (number of protons in the nucleus): 37. Atomic symbol (on the periodic table of elements): Rb. Atomic weight (average mass of the atom): 85.4678. Density: 0.886 ounces per cubic inch ...Web
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Story of Rubidium-82 and Advantages for Myocardial Perfusion …
Rubidium-82 has a long story, starting in 1954. After preclinical studies in dogs showing that myocardial uptake of this radionuclide was directly proportional to …Web
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Rubidium-82 generator yield and efficiency for PET perfusion …
Introduction. Rubidium-82 (82 Rb) is a widely used positron emission tomography (PET) tracer with a short half-life of ~ 75 seconds.1 Stress perfusion imaging with 82 Rb is used widely in cardiac PET centers for the assessment of known or suspected coronary artery disease.2 The short half-life of 82 Rb allows rapid sequential rest and …Web
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Strontium-82/rubidium-82 generator, method for producing a rubidium-82
These drawbacks make rubidium a better choice as a potassium-analog. Rubidium-82 is suitable for positron emission tomography, because Rubidium-82 is a positron emitter rendering higher quality images than conventional gamma camera imaging. Moreover Rubidium-82 is a radionuclide with an ultra-short half-life (t 1/2 =75s). This ultra-short …Web
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WO2010020596A1
The invention relates to a strontium-82/rubidium- 82 generator, comprising a column filled with a cationic exchanger loaded with strontium-82, and having an inlet and an outlet, and a liquid medium, wherein parts of the column, inlet and outlet coming into contact with the liquid medium are iron-free, preferably metal-free, to a method for producing rubidium …Web
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A systemic review of rubidium-82 PET contrasted with 99mTc …
Results: Eighteen original studies were selected and included in the final analysis out of 803 articles identified at the initial research. Overall, the mean value of …Web
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Radiopharmaceutical Agents for Myocardial Perfusion Imaging
Comparison of rubidium-82 positron emission tomography and thallium-201 SPECT imaging for detection of coronary artery disease. Am J Cardiol. 1991; 67: 1303–1310. Crossref Medline Google Scholar; 46 Yoshinaga K, Chow BJ, Williams K, Chen L, deKemp RA, Garrard L, Lok-Tin Szeto A, Aung M, Davies RA, Ruddy TD, Beanlands RS. What is …Web
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Fiche de données de sécurité
FDS – DRAXIMAGEMD Générateur Rubidium Rb 82 Jubilant DraxImage Inc. Page 5 of 5 Révision 3 2018 FE 16 15. INFORMATIONS SUR LA RÉGLEMENTATION SIMDUT: Cette fiche de données de sécurité (FDS) a été préparée conformément aux exigences du Système d'information sur les matières dangereuses utilisées au travail (2015) et du …Web
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10 January 2023 SUMMARY OF PRODUCT …
decays to rubidium-82 (82Rb), the daughter nuclide. Cardiogen-82 is a radionuclide generator of rubidium-82 (82Rb) containing strontium-82 (82Sr) adsorbed on stannic oxide in a chromatography column. It provides a means of obtaining, via elution, a sterile, non-pyrogenic injectable solution of rubidium-82 (82Rb) chloride.Web
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Myocardial perfusion scintigraphy using rubidium-82 positron …
82 Rb is produced from an 82 Sr– 82 Rb generator, which has a clinical life of 4–6 weeks. The 82 Rb is administered by remote intravenous infusion and the generator can be eluted with >90% yield every 10 min. 82 Rb is a potassium analogue and it crosses the capillary membrane rapidly, partly using the sodium–potassium exchange transporter.Web
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Reference ID: 3084430
in the rubidium Rb 82 chloride injection exceed limits. (5.1) Perform generator eluate tests: 1) Record each eluate volume, including waste and test volumes. (2.4) 2) Determine Rb …Web
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(PDF) Story of Rubidium-82 and Advantages for Myocardial
Rubidium-82 has a long story, starting in 1954. After preclinical studies in dogs showing that myocardial uptake of this radionuclide was directly proportional to myocardial blood flow (MBF ...Web
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BRAC-0005 PI
Rubidium-82 Dosage Rubidium chloride Rb 82 injection obtained from Cardiogen-82 (Rubidium Rb 82 Generator) is intended only for intravenous administration utilizing an appropriate infu-sion system that is labeled for use with the generator. The usual adult (70 kg) dose (single injection) is 1480 MBq (40 Rubidium Rb 82 Generator ®Web
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Current Status of Patient Radiation Exposure of Cardiac Positron
Previous data in normal subjects demonstrate an average radiation exposure of 0.9 mSv/20 mCi for Rb-82. 16 This translates to 2 to 6 mSv per study, depending on whether a 2-dimensional (2D) or 3D system is used. 8 Case et al 8 estimated achievable rubidium radiation exposure levels of 2 mSv for 3D systems and 4 mSv for 2D systems.Web
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Facts About Rubidium | Live Science
Rubidium is a silvery-white and very soft metal — and one of the most highly reactive elements on the periodic table. Rubidium has a density about one and a half times that of water and is...Web
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Ruby-fill (Rubidium Rb 82 Generator): Uses, Dosage, Side
Ruby-Fill (rubidium Rb 82 generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous use. Rubidium Rb 82 chloride injection is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional …Web
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Technical Considerations for Cardiac PET/CT | SpringerLink
PET Radiotracers for Myocardial Perfusion Imaging. Rubidium-82 (Rb-82): It is a monovalent cationic analogue of potassium and is produced in a commercially available generator by decay from strontium-82 attached to an elution column.It is the most commonly used radiopharmaceutical for myocardial perfusion imaging with PET, particularly in the …Web
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Cardiogen-82 (rubidium Rb 82 generator): Uses, Dosage, Side
Cardiogen-82 (rubidium Rb 82 generator) is a diagnostic aid used for Positron Emission Tomography (PET) imaging of the myocardium under rest or …Web
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EP2157583A1
Strontium-82/rubidium-82 generator, method for producing a rubidium-82 comprising diagnostic agent, said diagnostic agent and its use in medicineWeb
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HIGHLIGHTS OF PRESCRIBING INFORMATION …
rubidium Rb 82 chloride and complete the stress image acquisition. (2.3) -----DOSAGE FORMS AND STRENGTHS----- CardioGen-82 consists of strontium Sr 82 adsorbed on a hydrous stannic oxide column with an activity of 3,330 MBq to 5,550 MBq (90 millicuries to 150 millicuries) Sr 82 at calibration time. ...Web
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Rubidium | Rb (Element)
Twenty four isotopes of rubidium are known. Naturally occurring rubidium is made of two isotopes, 85 Rb and 87 Rb. Rubidium-87 is present to the extent of 27.85% in natural rubidium and is a beta emitter with a half-life of 4.9 x 10 10 years. Ordinary rubidium is sufficiently radioactive to expose a photographic film in about 30 to 60 days.Web
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Rubidium-82 generator yield and efficiency for PET perfusion
Introduction. Strontium-82/Rubidium-82 ( 82 Sr/ 82 Rb) generators are used widely for positron emission tomography (PET) imaging of myocardial perfusion. In this …Web
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A systemic review of rubidium-82 PET contrasted with 99mTc …
On the other hand, for 82-Rubidium-PET, the mean value of sensitivity and specificity for diagnosis of CAD was 81% and 81%, respectively. The accuracy of diagnostics of these imaging modalities was dependent on the radiotracers and stress agent used in these studies, with 99mTc-MIBI achieving the highest diagnostic value.Web
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Generator-produced rubidium-82 positron emission
Rubidium-82 (82 Rb) is a PET myocardial perfusion tracer that is produced with a strontium-82 (82 Sr)/ 82 Rb generator and is widely used for the diagnosis of CAD in centers without immediate access to an on-site cyclotron [3], [4]. Therefore, 82 Rb perfusion studies could be applied in larger populations [5], [6].Web
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Rubidium-82 | Rb | CID 5464265
Rubidium-82 | Rb | CID 5464265 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ...Web
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